Product Name :
Regaloside A
Description:
Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity.
CAS:
114420-66-5
Molecular Weight:
400.38
Formula:
C18H24O10
Chemical Name:
(2S)-2-hydroxy-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate
Smiles :
OC1C=CC(=CC=1)/C=C/C(=O)OC[C@@H](O)COC1OC(CO)C(O)C(O)C1O
InChiKey:
PADHSFRQMFRWLS-MUWVXHEGSA-N
InChi :
InChI=1S/C18H24O10/c19-7-13-15(23)16(24)17(25)18(28-13)27-9-12(21)8-26-14(22)6-3-10-1-4-11(20)5-2-10/h1-6,12-13,15-21,23-25H,7-9H2/b6-3+/t12-,13?,15?,16?,17?,18?/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Linperlisib} site|{Linperlisib} PI3K/Akt/mTOR|{Linperlisib} Protocol|{Linperlisib} In Vitro|{Linperlisib} manufacturer|{Linperlisib} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{MARK-IN-2} web|{MARK-IN-2} Epigenetics|{MARK-IN-2} TGF-beta/Smad|{MARK-IN-2} Biological Activity|{MARK-IN-2} In Vivo|{MARK-IN-2} custom synthesis}
Additional information:
Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.PMID:23539298 0% at 160 ppm. Regaloside A has anti-inflammatory activity.|Product information|CAS Number: 114420-66-5|Molecular Weight: 400.38|Formula: C18H24O10|Chemical Name: (2S)-2-hydroxy-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate|Smiles: OC1C=CC(=CC=1)/C=C/C(=O)OC[C@@H](O)COC1OC(CO)C(O)C(O)C1O|InChiKey: PADHSFRQMFRWLS-MUWVXHEGSA-N|InChi: InChI=1S/C18H24O10/c19-7-13-15(23)16(24)17(25)18(28-13)27-9-12(21)8-26-14(22)6-3-10-1-4-11(20)5-2-10/h1-6,12-13,15-21,23-25H,7-9H2/b6-3+/t12-,13?,15?,16?,17?,18?/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Regaloside A (50 μg/mL; 2 hours) inhibits the expression of iNOS to 70.3 decreasing COX-2 expression to 131.6 in Raw 264.7 cells treated with LPS (1 μg/ml; pretreatment for 15 min). Regaloside A decreases the ratio of p-p65/p-65 to 40.7. Regaloside A (50 μg/mL; pretreatment for 2 hours) decreases the expression of VCAM-1 to 48.6 in HASMCs with TNF-a (10 ng/ml; for 12 h).|Products are for research use only. Not for human use.|
