Product Name :
20-O-Demethyl-AP3
Description:
20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic.
CAS:
72902-38-6
Molecular Weight:
621.12
Formula:
C31H41ClN2O9
Chemical Name:
(1S,2R,3S,5S,6S,20R,21S)-11-chloro-12,21-dihydroxy-20-methoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1¹⁰,¹⁴.0³,⁵]hexacosa-10(26),11,13,16,18-pentaen-6-yl 2-methylpropanoate
Smiles :
C[C@@]12O[C@H]1[C@H](C)[C@@H]1C[C@@](O)(NC(=O)O1)[C@@H](C=CC=C(C)CC1=CC(O)=C(Cl)C(=C1)N(C)C(=O)C[C@@H]2OC(=O)C(C)C)OC |c:19,t:17|
InChiKey:
YQVKSZNVVCIETH-AJWAOHEYSA-N
InChi :
InChI=1S/C31H41ClN2O9/c1-16(2)28(37)42-24-14-25(36)34(6)20-12-19(13-21(35)26(20)32)11-17(3)9-8-10-23(40-7)31(39)15-22(41-29(38)33-31)18(4)27-30(24,5)43-27/h8-10,12-13,16,18,22-24,27,35,39H,11,14-15H2,1-7H3,(H,33,38)/b10-8-,17-9-/t18-,22+,23-,24+,27+,30+,31+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Anti-HA Affinity Gel} MedChemExpress|{Anti-HA Affinity Gel} Epigenetics|{Anti-HA Affinity Gel} Protocol|{Anti-HA Affinity Gel} Purity|{Anti-HA Affinity Gel} supplier}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Andecaliximab} medchemexpress|{Andecaliximab} Metabolic Enzyme/Protease|{Andecaliximab} Biological Activity|{Andecaliximab} Purity|{Andecaliximab} supplier|{Andecaliximab} Epigenetics}
Additional information:
20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3.PMID:24220671 Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic.|Product information|CAS Number: 72902-38-6|Molecular Weight: 621.12|Formula: C31H41ClN2O9|Chemical Name: (1S,2R,3S,5S,6S,20R,21S)-11-chloro-12,21-dihydroxy-20-methoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1¹⁰,¹⁴.0³,⁵]hexacosa-10(26),11,13,16,18-pentaen-6-yl 2-methylpropanoate|Smiles: C[C@@]12O[C@H]1[C@H](C)[C@@H]1C[C@@](O)(NC(=O)O1)[C@@H](C=CC=C(C)CC1=CC(O)=C(Cl)C(=C1)N(C)C(=O)C[C@@H]2OC(=O)C(C)C)OC |c:19,t:17||InChiKey: YQVKSZNVVCIETH-AJWAOHEYSA-N|InChi: InChI=1S/C31H41ClN2O9/c1-16(2)28(37)42-24-14-25(36)34(6)20-12-19(13-21(35)26(20)32)11-17(3)9-8-10-23(40-7)31(39)15-22(41-29(38)33-31)18(4)27-30(24,5)43-27/h8-10,12-13,16,18,22-24,27,35,39H,11,14-15H2,1-7H3,(H,33,38)/b10-8-,17-9-/t18-,22+,23-,24+,27+,30+,31+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
