Product Name :
FIN56
Description:
FIN56 is a specific inducer of ferroptosis.
CAS:
1083162-61-1
Molecular Weight:
517.66
Formula:
C25H31N3O5S2
Chemical Name:
N2,N7-Dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide
Smiles :
ON=C1C2=CC(=CC=C2C2=CC=C(C=C21)S(=O)(=O)NC1CCCCC1)S(=O)(=O)NC1CCCCC1
InChiKey:
JLCFMMIWBSZOIS-UHFFFAOYSA-N
InChi :
InChI=1S/C25H31N3O5S2/c29-26-25-23-15-19(34(30,31)27-17-7-3-1-4-8-17)11-13-21(23)22-14-12-20(16-24(22)25)35(32,33)28-18-9-5-2-6-10-18/h11-18,27-29H,1-10H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
FIN56 is a specific inducer of ferroptosis.|Product information|CAS Number: 1083162-61-1|Molecular Weight: 517.66|Formula: C25H31N3O5S2|Synonym:|FIN-56|FIN56|FIN 56|Chemical Name: N2,N7-Dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide|Smiles: ON=C1C2=CC(=CC=C2C2=CC=C(C=C21)S(=O)(=O)NC1CCCCC1)S(=O)(=O)NC1CCCCC1|InChiKey: JLCFMMIWBSZOIS-UHFFFAOYSA-N|InChi: InChI=1S/C25H31N3O5S2/c29-26-25-23-15-19(34(30,31)27-17-7-3-1-4-8-17)11-13-21(23)22-14-12-20(16-24(22)25)35(32,33)28-18-9-5-2-6-10-18/h11-18,27-29H,1-10H2|Technical Data|Appearance: Solid Power.|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined.|HS Tariff Code: 382200|How to use|In Vitro:|FIN56 (5 μM) can trigger ferroptosis by inhibition of glutathione peroxidase 4 (GPX4). FIN56 (5 μM, 10 hours) depletes GPX4 protein in HT-1080 cells.{{Abciximab} site|{Abciximab} Cytoskeleton|{Abciximab} Purity & Documentation|{Abciximab} In stock|{Abciximab} manufacturer|{Abciximab} Autophagy} |References:|Shimada K, Skouta R, Kaplan A, Yang WS, Hayano M, Dixon SJ, Brown LM, Valenzuela CA, Wolpaw AJ, Stockwell BR.{{Monoethyl phthalate} MedChemExpress|{Monoethyl phthalate} Drug Metabolite|{Monoethyl phthalate} Activator|{Monoethyl phthalate} Protocol|{Monoethyl phthalate} In Vitro|{Monoethyl phthalate} manufacturer} Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.PMID:25016614 Nat Chem Biol. 2016 Jul;12(7):497-503. doi: 10.1038/nchembio.2079. Epub 2016 May 9. PubMed PMID: 27159577; PubMed Central PMCID: PMC4920070.Kolasa A. [Epididymis in an experimental model of DHT deficiency: immunolocalization of ERalpha and ERbeta in rat epididymal epithelial cells. In vivo and in vitro studies]. Ann Acad Med Stetin. 2006;52(2):13-21; discussion 21. Polish. PubMed PMID: 17633123.Products are for research use only. Not for human use.|
