Product Name :
Anethole trithione
Description:
Anethole trithione, a sulfur heterocyclic choleretic, is a bile secretion-stimulating agent. Anethole trithione enhances salivary secretion and increases mAChRs, and can be used for dry mouth research.
CAS:
532-11-6
Molecular Weight:
240.36
Formula:
C10H8OS3
Chemical Name:
5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione
Smiles :
COC1C=CC(=CC=1)C1=CC(=S)SS1
InChiKey:
KYLIZBIRMBGUOP-UHFFFAOYSA-N
InChi :
InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Anethole trithione, a sulfur heterocyclic choleretic, is a bile secretion-stimulating agent. Anethole trithione enhances salivary secretion and increases mAChRs, and can be used for dry mouth research.|Product information|CAS Number: 532-11-6|Molecular Weight: 240.36|Formula: C10H8OS3|Chemical Name: 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione|Smiles: COC1C=CC(=CC=1)C1=CC(=S)SS1|InChiKey: KYLIZBIRMBGUOP-UHFFFAOYSA-N|InChi: InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 12.5 mg/mL (52.01 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Evobrutinib} medchemexpress|{Evobrutinib} Protein Tyrosine Kinase/RTK|{Evobrutinib} Protocol|{Evobrutinib} Formula|{Evobrutinib} custom synthesis|{Evobrutinib} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Pepinemab} MedChemExpress|{Pepinemab} Technical Information|{Pepinemab} Purity|{Pepinemab} supplier|{Pepinemab} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23557924 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Anethole trithione, a slow-releasing H2S donor, is a bile secretion-stimulating drug or cholagogue that protects the liver via an increase in glutathione levels and phase II detoxifying enzymes. Anethole trithione is a potentially efficacious chemoprevention agent for lung cancer and exerts chemopreventive effects in several target organs, such as the liver and colon, by increasing the detoxification rate of carcinogens in these target organs. Anethole trithione protects blood-brain barrier integrity following cerebral ischemia.|In Vivo:|Chronic treatment with Anethole trithione increases the salivary secretion from the rat submaxillary gland induced by electrical stimulation of the parasympathetic nerve and by injection of pilocarpine. In parallel with the enhancement of the salivary secretion, the number of the muscarinic acetylcholine receptors is significantly increased.|Products are for research use only. Not for human use.|
