Product Name :
PF-04447943
Description:
PF-04447943 is a potent and selective brain penetrant PDE9A inhibitor for the treatment of cognitive disorders. PF-04447943 attenuates a scopolamine-induced deficit in a novel rodent attention task. PF-04447943 enhances synaptic plasticity and cognitive function in rodents.
CAS:
1082744-20-4
Molecular Weight:
395.46
Formula:
C20H25N7O2
Chemical Name:
6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-1-(oxan-4-yl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one
Smiles :
C[C@@H]1CN(C[C@H]1C1NC(=O)C2C=NN(C3CCOCC3)C=2N=1)CC1N=CC=CN=1
InChiKey:
IWXUVYOOUMLUTQ-CZUORRHYSA-N
InChi :
InChI=1S/C20H25N7O2/c1-13-10-26(12-17-21-5-2-6-22-17)11-16(13)18-24-19-15(20(28)25-18)9-23-27(19)14-3-7-29-8-4-14/h2,5-6,9,13-14,16H,3-4,7-8,10-12H2,1H3,(H,24,25,28)/t13-,16-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PF-04447943 is a potent and selective brain penetrant PDE9A inhibitor for the treatment of cognitive disorders.{{Ginsenoside Rb2} site|{Ginsenoside Rb2} Anti-infection|{Ginsenoside Rb2} Purity & Documentation|{Ginsenoside Rb2} Formula|{Ginsenoside Rb2} manufacturer|{Ginsenoside Rb2} Cancer} PF-04447943 attenuates a scopolamine-induced deficit in a novel rodent attention task. PF-04447943 enhances synaptic plasticity and cognitive function in rodents.{{Glipizide} MedChemExpress|{Glipizide} Membrane Transporter/Ion Channel|{Glipizide} Protocol|{Glipizide} Data Sheet|{Glipizide} custom synthesis|{Glipizide} Epigenetic Reader Domain} |Product information|CAS Number: 1082744-20-4|Molecular Weight: 395.PMID:23880095 46|Formula: C20H25N7O2|Chemical Name: 6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-1-(oxan-4-yl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one|Smiles: C[C@@H]1CN(C[C@H]1C1NC(=O)C2C=NN(C3CCOCC3)C=2N=1)CC1N=CC=CN=1|InChiKey: IWXUVYOOUMLUTQ-CZUORRHYSA-N|InChi: InChI=1S/C20H25N7O2/c1-13-10-26(12-17-21-5-2-6-22-17)11-16(13)18-24-19-15(20(28)25-18)9-23-27(19)14-3-7-29-8-4-14/h2,5-6,9,13-14,16H,3-4,7-8,10-12H2,1H3,(H,24,25,28)/t13-,16-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
