Ord order disord order No. of proteins Typical protein length
Ord order disord order No. of proteins Typical protein length (AAregion) A protein is thought of completely Anemoside B4 chemical information disordered if all of its AA are predicted to be disordered (by predictor).The typical quantity of disordered regions (of L AA) by protein and COG of proteins for archaea and bacteria, is presented on the web web-site (link L). The average variety of disordered regions of L AA in all the proteins coded by COGs isby protein. The largest typical variety of disordered regions is identified within the proteins coded by COG L in archaea plus the proteins coded by COG V in bacteria , using the exception of poorly populated COGs W and Z . For disordered regions of L , AA, the typical variety of disordered regions would be the highest for proteins coded by COG N, for each archaea and bacteria, once more with all the exception of poorly populated COGs W and Z. In general, the highest typical variety of disordered regions is located in proteins coded by COGs in the Cp functional group (COGs: D, M, N, O, T, U, V, W), followed by Isp (COGs: A, B, J, K, L), followed by Me (COGs: C, E, F, G, H, I, P, Q),Pavlovi-Lazeti et al. BMC Bioinformatics , : http:biomedcentral-Page ofTable Archaea and bacteria by phylaSuperkingdom Archaea Phylum Crenarchaeota Euryarchaeota Nanoarchaeota Archaea total: Bacteria Actinobacteria Alphaproteobacteria Aquificae BacteroidetesChlorobi Betaproteobacteria Chlamydiae Verrucomicrobia Chloroflexi Cyanobacteria Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria Firmicutes Fusobacteria Gammaproteobacteria Planctomycetes Spirochaetes Thermotogae Bacteria total: organisms proteins proteins proteins proteins proteins , , Number of organisms, quantity of proteins, quantity and percentage of proteins with disordered amino acids, number and percentage of disordered proteins.followed by Computer (COGs: R, S). Proteins coded by genes N. C. have a low variety of disordered regions of any length. The highest typical number of disordered regions of L , AA, by protein, in most phyla, is discovered in COGs N (Cp) and L (Isp).The imply worth of each of the typical numbers of disordered regions in proteins, by COGs, for regions of L AA in bacteria is with STD to ensure that COGs deviating far more than STD from the mean worth are W and Z (higher average); the N. C. group of proteinsFigure The percentage of disordered and ordered regions of specific length in archaea and bacteria. The PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24465392?dopt=Abstract percentage is calculated relative to the total number of regions from the corresponding kind (disordered, ordered).Pavlovi-Lazeti et al. BMC Bioinformatics , : http:biomedcentral-Page ofsignificantly deviates with a low typical. Archaea are much far more steady: imply value iswith STD For longer disordered regions, the only deviating COG in bacteria is W and in archaea the COGs K, L, T, V, P (higher average, see the web internet site, hyperlink L).Variety of disordered regions per AA by COGs of proteinsThe average number of disordered regions per AA by COGs of proteins neutralizes effects of protein length. It is depicted, for diverse lengths of disordered regions, in FigureFor bacteria, the average number of disordered regions of L AA per AA by COGs equalswith STD although in archaea the corresponding values are respectively. Deviating COGs converge (more than increasing length of disordered regions) to W and N in bacteria and just a singleton COG W (with just protein) in archaea. Proteins classified in the functional group of Metabolism COGs, show again the lowest d.