Product Name :
Dooku1
Description:
Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibited 2 μM Yoda1-induced Ca2+-entry with IC50 values of 1.3 μM (in HEK 293 cells) and 1.5 μM (in HUVECs). Dooku1 inhibits Yoda1-induced relaxation of aorta.
CAS:
2253744-54-4
Molecular Weight:
326.20
Formula:
C13H9Cl2N3OS
Chemical Name:
2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole
Smiles :
ClC1C=CC=C(Cl)C=1CSC1=NN=C(O1)C1=CC=CN1
InChiKey:
MNPOBXLPCWFONX-UHFFFAOYSA-N
InChi :
InChI=1S/C13H9Cl2N3OS/c14-9-3-1-4-10(15)8(9)7-20-13-18-17-12(19-13)11-5-2-6-16-11/h1-6,16H,7H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibited 2 μM Yoda1-induced Ca2+-entry with IC50 values of 1.{{D(+)-Galactosamine} MedChemExpress|{D(+)-Galactosamine} Biological Activity|{D(+)-Galactosamine} In Vitro|{D(+)-Galactosamine} manufacturer|{D(+)-Galactosamine} Epigenetics} 3 μM (in HEK 293 cells) and 1.{{Lincomycin hydrochloride} site|{Lincomycin hydrochloride} Antibiotic|{Lincomycin hydrochloride} Purity & Documentation|{Lincomycin hydrochloride} Data Sheet|{Lincomycin hydrochloride} custom synthesis|{Lincomycin hydrochloride} Epigenetics} 5 μM (in HUVECs).PMID:32667978 Dooku1 inhibits Yoda1-induced relaxation of aorta.|Product information|CAS Number: 2253744-54-4|Molecular Weight: 326.20|Formula: C13H9Cl2N3OS|Chemical Name: 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole|Smiles: ClC1C=CC=C(Cl)C=1CSC1=NN=C(O1)C1=CC=CN1|InChiKey: MNPOBXLPCWFONX-UHFFFAOYSA-N|InChi: InChI=1S/C13H9Cl2N3OS/c14-9-3-1-4-10(15)8(9)7-20-13-18-17-12(19-13)11-5-2-6-16-11/h1-6,16H,7H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (383.20 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
