Product Name :
KHK-IN-1 hydrochloride
CAS No.:
1303470-48-5
Purity :
98.05%
Shipping:
Room temperature in the continental U.S. Other areas may vary.
Storage :
In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
SMILES:
[H]Cl.CSC(C=CC=C1)=C1NC2=NC(N3CCNCC3)=NC4=C2N=CN=C4NCC5CC5
Product Description :
KHK-IN-1 hydrochloride (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM; F=34%). KHK-IN-1 hydrochloride inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 hydrochloride has potential for the study of diabetes and obesity.{{842148-40-7} site|{842148-40-7} Purity & Documentation|{842148-40-7} In Vivo|{842148-40-7} custom synthesis}
Formula:
C21H27ClN8S
Molecular Weight :
459.{{202668-42-6} web|{202668-42-6} Biological Activity|{202668-42-6} References|{202668-42-6} manufacturer} 01
Synonyms:
Additional Information:
|CAS No.PMID:31082100 1303470-48-5 ; |Formula C21H27ClN8S ; |Molecular Weight 459.01 ; |SMILES [H]Cl.CSC(C=CC=C1)=C1NC2=NC(N3CCNCC3)=NC4=C2N=CN=C4NCC5CC5 ; |Target Ketohexokinase ; |Product Description KHK-IN-1 hydrochloride (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM; F=34%). KHK-IN-1 hydrochloride inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 hydrochloride has potential for the study of diabetes and obesity. ; |Format Solid ; |Color Light yellow to yellow ; |Purity 98.05% ; |Shipping Room temperature in the continental U.S. Other areas may vary. ; |Storage In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) ; |Solubility Overview Soluble in DMSO
