Product Name :
Anti-ITGB7, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-ITGB7, Human antibody is designed for detecting human ITGB7 specifically. Based on ELISA and/or FCM, Anti-ITGB7, Human antibody reacts with human ITGB7 specifically. | Immunogen: Recombinant human ITGB7 | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human ITGB7 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.{{1638750-95-4} MedChemExpress|{1638750-95-4} Technical Information|{1638750-95-4} Data Sheet|{1638750-95-4} manufacturer} 1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324).{{122111-03-9} MedChemExpress|{122111-03-9} Purity & Documentation|{122111-03-9} Formula|{122111-03-9} custom synthesis} Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Description2 :
Anti-ITGB7, Human antibody is designed for detecting human ITGB7 specifically.PMID:30000739 Based on ELISA and/or FCM, Anti-ITGB7, Human antibody reacts with human ITGB7 specifically.
Immunogen:
Recombinant human ITGB7
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.
