Product Name :
Filgotinib (GLPG0634)
CAS No.:
1206161-97-8
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
O=C(NC1=N[N]2C(=N1)C=CC=C2C3=CC=C(CN4CC[S](=O)(=O)CC4)C=C3)C5CC5
Product Description :
Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.{{302-79-4} MedChemExpress|{302-79-4} Biological Activity|{302-79-4} Data Sheet|{302-79-4} custom synthesis} Phase 2.{{1820563-84-5} MedChemExpress|{1820563-84-5} Purity & Documentation|{1820563-84-5} In Vitro|{1820563-84-5} custom synthesis}
Formula:
C21H23N5O3S
Molecular Weight :
425.5
Synonyms:
Additional Information:
|CAS No.PMID:30855871 1206161-97-8 ; |Formula C21H23N5O3S ; |Molecular Weight 425.5 ; |SMILES O=C(NC1=N[N]2C(=N1)C=CC=C2C3=CC=C(CN4CC[S](=O)(=O)CC4)C=C3)C5CC5 ; |Product Description Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO