Product Name :
PNU-177864 hydrochloride
Description:
PNU-177864 hydrochloride is a potent, selective and orally active dopamine D3 receptor antagonist. PNU-177864 hydrochloride is structurally consistent with a cationic amphiphilic drug (CAD) and induces phospholipidosis in vivo. PNU-177864 hydrochloride antischizophrenic activity.
CAS:
1783978-03-9
Molecular Weight:
438.89
Formula:
C18H22ClF3N2O3S
Chemical Name:
N-{4-[2-(propylamino)ethyl]phenyl}-4-(trifluoromethoxy)benzene-1-sulfonamide hydrochloride
Smiles :
Cl.CCCNCCC1=CC=C(C=C1)NS(=O)(=O)C1C=CC(=CC=1)OC(F)(F)F
InChiKey:
UOMDLHQTLPWCCE-UHFFFAOYSA-N
InChi :
InChI=1S/C18H21F3N2O3S.ClH/c1-2-12-22-13-11-14-3-5-15(6-4-14)23-27(24,25)17-9-7-16(8-10-17)26-18(19,20)21;/h3-10,22-23H,2,11-13H2,1H3;1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Zidovudine} MedChemExpress|{Zidovudine} CRISPR/Cas9|{Zidovudine} Purity & Documentation|{Zidovudine} Formula|{Zidovudine} manufacturer|{Zidovudine} Epigenetic Reader Domain}
Additional information:
PNU-177864 hydrochloride is a potent, selective and orally active dopamine D3 receptor antagonist.{{Spesolimab} web|{Spesolimab} Interleukin Related|{Spesolimab} Protocol|{Spesolimab} Description|{Spesolimab} supplier|{Spesolimab} Autophagy} PNU-177864 hydrochloride is structurally consistent with a cationic amphiphilic drug (CAD) and induces phospholipidosis in vivo. PNU-177864 hydrochloride antischizophrenic activity.|Product information|CAS Number: 1783978-03-9|Molecular Weight: 438.89|Formula: C18H22ClF3N2O3S|Chemical Name: N-{4-[2-(propylamino)ethyl]phenyl}-4-(trifluoromethoxy)benzene-1-sulfonamide hydrochloride|Smiles: Cl.CCCNCCC1=CC=C(C=C1)NS(=O)(=O)C1C=CC(=CC=1)OC(F)(F)F|InChiKey: UOMDLHQTLPWCCE-UHFFFAOYSA-N|InChi: InChI=1S/C18H21F3N2O3S.ClH/c1-2-12-22-13-11-14-3-5-15(6-4-14)23-27(24,25)17-9-7-16(8-10-17)26-18(19,20)21;/h3-10,22-23H,2,11-13H2,1H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23291014 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|PNU-177864 (12.5-200 mg/kg; oral gavage; daily; for 2-4 weeks; Sprague-Dawley rats) treatment induces phospholipidosis in unusual target organs in dogs or rats including epididymis, pituitary, and hair follicles.|Products are for research use only. Not for human use.|
