Product Name :
BQ-788
Description:
BQ788 is a endothelin B receptor antagonist. BQ788 attenuates stab wound injury-induced reactive astrocytes in rat brain. BQ788 were well tolerated and showed signs of directly and indirectly reducing the viability of melanoma cells.
CAS:
173326-37-9
Molecular Weight:
641.80
Formula:
C34H51N5O7
Chemical Name:
(2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid
Smiles :
CCCC[C@@H](NC(=O)[C@@H](CC1=CN(C2=CC=CC=C12)C(=O)OC)NC(=O)[C@H](CC(C)(C)C)NC(=O)N1[C@H](C)CCC[C@@H]1C)C(O)=O
InChiKey:
LPAHKJMGDSJDRG-DJYQTOCQSA-N
InChi :
InChI=1S/C34H51N5O7/c1-8-9-16-25(31(42)43)35-29(40)26(18-23-20-38(33(45)46-7)28-17-11-10-15-24(23)28)36-30(41)27(19-34(4,5)6)37-32(44)39-21(2)13-12-14-22(39)3/h10-11,15,17,20-22,25-27H,8-9,12-14,16,18-19H2,1-7H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43)/t21-,22+,25-,26-,27+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
BQ788 is a endothelin B receptor antagonist.{{Thymidine 5′-monophosphate p-nitrophenyl ester} web|{Thymidine 5′-monophosphate p-nitrophenyl ester} Metabolic Enzyme/Protease|{Thymidine 5′-monophosphate p-nitrophenyl ester} TGF-beta/Smad|{Thymidine 5′-monophosphate p-nitrophenyl ester} Biological Activity|{Thymidine 5′-monophosphate p-nitrophenyl ester} Description|{Thymidine 5′-monophosphate p-nitrophenyl ester} custom synthesis} BQ788 attenuates stab wound injury-induced reactive astrocytes in rat brain.{{Amlodipine besylate} medchemexpress|{Amlodipine besylate} Calcium Channel|{Amlodipine besylate} Biological Activity|{Amlodipine besylate} Formula|{Amlodipine besylate} supplier|{Amlodipine besylate} Epigenetics} BQ788 were well tolerated and showed signs of directly and indirectly reducing the viability of melanoma cells.PMID:24458656 |Product information|CAS Number: 173326-37-9|Molecular Weight: 641.80|Formula: C34H51N5O7|Chemical Name: (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid|Smiles: CCCC[C@@H](NC(=O)[C@@H](CC1=CN(C2=CC=CC=C12)C(=O)OC)NC(=O)[C@H](CC(C)(C)C)NC(=O)N1[C@H](C)CCC[C@@H]1C)C(O)=O|InChiKey: LPAHKJMGDSJDRG-DJYQTOCQSA-N|InChi: InChI=1S/C34H51N5O7/c1-8-9-16-25(31(42)43)35-29(40)26(18-23-20-38(33(45)46-7)28-17-11-10-15-24(23)28)36-30(41)27(19-34(4,5)6)37-32(44)39-21(2)13-12-14-22(39)3/h10-11,15,17,20-22,25-27H,8-9,12-14,16,18-19H2,1-7H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43)/t21-,22+,25-,26-,27+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
