Product Name :
TG 100572 Hydrochloride
Description:
TG-100572 is a potent and selective VEGFR2/Src kinase inhibitor. TG100572 inhibits Src kinases and selected receptor tyrosine kinases, induced apoptosis of proliferating endothelial cells in vitro. TG100572 inhibits downstream molecules involved in the vascular endothelial growth factor (VEGF) signaling pathway resulted in markedly diminished levels of HSV-induced angiogenesis and significantly reduced the severity of SK lesions..
CAS:
867331-64-4
Molecular Weight:
512.43
Formula:
C26H27Cl2N5O2
Chemical Name:
4-chloro-3-[5-methyl-3-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)-1,2,4-benzotriazin-7-yl]phenol hydrochloride
Smiles :
Cl.CC1=CC(=CC2=NN=C(NC3C=CC(=CC=3)OCCN3CCCC3)N=C21)C1=CC(O)=CC=C1Cl
InChiKey:
NVINBIHNVAYEND-UHFFFAOYSA-N
InChi :
InChI=1S/C26H26ClN5O2.ClH/c1-17-14-18(22-16-20(33)6-9-23(22)27)15-24-25(17)29-26(31-30-24)28-19-4-7-21(8-5-19)34-13-12-32-10-2-3-11-32;/h4-9,14-16,33H,2-3,10-13H2,1H3,(H,28,29,31);1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
TG-100572 is a potent and selective VEGFR2/Src kinase inhibitor. TG100572 inhibits Src kinases and selected receptor tyrosine kinases, induced apoptosis of proliferating endothelial cells in vitro. TG100572 inhibits downstream molecules involved in the vascular endothelial growth factor (VEGF) signaling pathway resulted in markedly diminished levels of HSV-induced angiogenesis and significantly reduced the severity of SK lesions..|Product information|CAS Number: 867331-64-4|Molecular Weight: 512.43|Formula: C26H27Cl2N5O2|Chemical Name: 4-chloro-3-[5-methyl-3-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)-1,2,4-benzotriazin-7-yl]phenol hydrochloride|Smiles: Cl.{{Bazedoxifene} medchemexpress|{Bazedoxifene} Estrogen Receptor/ERR|{Bazedoxifene} Purity & Documentation|{Bazedoxifene} Data Sheet|{Bazedoxifene} custom synthesis|{Bazedoxifene} Autophagy} CC1=CC(=CC2=NN=C(NC3C=CC(=CC=3)OCCN3CCCC3)N=C21)C1=CC(O)=CC=C1Cl|InChiKey: NVINBIHNVAYEND-UHFFFAOYSA-N|InChi: InChI=1S/C26H26ClN5O2.{{Tebotelimab} MedChemExpress|{Tebotelimab} Immunology/Inflammation|{Tebotelimab} Purity & Documentation|{Tebotelimab} References|{Tebotelimab} manufacturer|{Tebotelimab} Epigenetic Reader Domain} ClH/c1-17-14-18(22-16-20(33)6-9-23(22)27)15-24-25(17)29-26(31-30-24)28-19-4-7-21(8-5-19)34-13-12-32-10-2-3-11-32;/h4-9,14-16,33H,2-3,10-13H2,1H3,(H,28,29,31);1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23962101 |Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
