Product Name :
Levosimendan
Description:
Levosimendan is a calcium sensitizer that can cause increased cardiac contractility by binding troponin C, promotes vasodilation by activating ATP-sensitive potassium channels on vascular smooth muscle cells, and performs a cardioprotective function by prompting the opening of mitochondrial potassium channels in cardiomyocytes. It also has been reported to inhibit phosphodiesterases 3 and 4 in left ventricular cardiac tissue.
CAS:
141505-33-1
Molecular Weight:
280.28
Formula:
C14H12N6O
Chemical Name:
1-cyano-N-{4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl]phenyl}methanecarbohydrazonoyl cyanide
Smiles :
C[C@@H]1CC(=O)NN=C1C1C=CC(=CC=1)NN=C(C#N)C#N
InChiKey:
WHXMKTBCFHIYNQ-SECBINFHSA-N
InChi :
InChI=1S/C14H12N6O/c1-9-6-13(21)19-20-14(9)10-2-4-11(5-3-10)17-18-12(7-15)8-16/h2-5,9,17H,6H2,1H3,(H,19,21)/t9-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Levosimendan is a calcium sensitizer that can cause increased cardiac contractility by binding troponin C, promotes vasodilation by activating ATP-sensitive potassium channels on vascular smooth muscle cells, and performs a cardioprotective function by prompting the opening of mitochondrial potassium channels in cardiomyocytes. It also has been reported to inhibit phosphodiesterases 3 and 4 in left ventricular cardiac tissue.{{Laquinimod} site|{Laquinimod} Apoptosis|{Laquinimod} Protocol|{Laquinimod} Data Sheet|{Laquinimod} supplier|{Laquinimod} Autophagy} |Product information|CAS Number: 141505-33-1|Molecular Weight: 280.{{Osimertinib} medchemexpress|{Osimertinib} JAK/STAT Signaling|{Osimertinib} Purity & Documentation|{Osimertinib} Description|{Osimertinib} custom synthesis|{Osimertinib} Autophagy} 28|Formula: C14H12N6O|Chemical Name: 1-cyano-N-{4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl]phenyl}methanecarbohydrazonoyl cyanide|Smiles: C[C@@H]1CC(=O)NN=C1C1C=CC(=CC=1)NN=C(C#N)C#N|InChiKey: WHXMKTBCFHIYNQ-SECBINFHSA-N|InChi: InChI=1S/C14H12N6O/c1-9-6-13(21)19-20-14(9)10-2-4-11(5-3-10)17-18-12(7-15)8-16/h2-5,9,17H,6H2,1H3,(H,19,21)/t9-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23937941 |Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
