Product Name :
BTTAA
Description:
BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF.
CAS:
1334179-85-9
Molecular Weight:
430.51
Formula:
C19H30N10O2
Chemical Name:
2-[4-({bis[(1-tert-butyl-1H-1,2,3-triazol-4-yl)methyl]amino}methyl)-1H-1,2,3-triazol-1-yl]acetic acid
Smiles :
CC(C)(C)N1C=C(CN(CC2=CN(CC(O)=O)N=N2)CC2=CN(N=N2)C(C)(C)C)N=N1
InChiKey:
MGQYHUDOWOGSQI-UHFFFAOYSA-N
InChi :
InChI=1S/C19H30N10O2/c1-18(2,3)28-11-15(21-24-28)8-26(7-14-10-27(23-20-14)13-17(30)31)9-16-12-29(25-22-16)19(4,5)6/h10-12H,7-9,13H2,1-6H3,(H,30,31)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF.{{Vipivotide tetraxetan} site|{Vipivotide tetraxetan} Drug-Linker Conjugates for ADC|{Vipivotide tetraxetan} Biological Activity|{Vipivotide tetraxetan} Data Sheet|{Vipivotide tetraxetan} supplier|{Vipivotide tetraxetan} Cancer} |Product information|CAS Number: 1334179-85-9|Molecular Weight: 430.{{Calcitonin (human)} site|{Calcitonin (human)} Neuronal Signaling|{Calcitonin (human)} Purity & Documentation|{Calcitonin (human)} Data Sheet|{Calcitonin (human)} custom synthesis|{Calcitonin (human)} Epigenetics} 51|Formula: C19H30N10O2|Chemical Name: 2-[4-({bis[(1-tert-butyl-1H-1,2,3-triazol-4-yl)methyl]amino}methyl)-1H-1,2,3-triazol-1-yl]acetic acid|Smiles: CC(C)(C)N1C=C(CN(CC2=CN(CC(O)=O)N=N2)CC2=CN(N=N2)C(C)(C)C)N=N1|InChiKey: MGQYHUDOWOGSQI-UHFFFAOYSA-N|InChi: InChI=1S/C19H30N10O2/c1-18(2,3)28-11-15(21-24-28)8-26(7-14-10-27(23-20-14)13-17(30)31)9-16-12-29(25-22-16)19(4,5)6/h10-12H,7-9,13H2,1-6H3,(H,30,31)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : 5 mg/mL (11.PMID:23659187 61 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|BTTAA is a Cu(I)-stabilizing ligand. Using the Glu18AzF mutant of ubiquitin as a model system with C3-Tm3+ and C4-Tm3+, Cu-BTTAA performs significantly better as a catalyst than Cu-THPTA or Cu-TBTA. BTTAA proves to perform much better than THPTA (tris[(1-hydroxy-propyl-1H-1,2,3-triazol-4-yl)methyl]amine) or TBTA (tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine).|Products are for research use only. Not for human use.|
