Blisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.1. Introduction Identifying biomarkers could aid in clinical decision making considering the fact that it makes it possible for personalised medicine in oncology. There are actually two key types of biomarkers: predictive markers, which direct the usage of modified therapies, and prognostic markers, which assist the evaluation of Biotin-NHS Epigenetics malignancy features and clinical trial planning. With the availability of biomarkers, managing cancer therapy has revolved about the tenets of genetics and proteomics. Since then, there’s a expanding interest in expanding the application of biomarkers in managing cancer patients. Additionally, the clinical possible of monitoring disease using immunohistochemistry is nicely established, especially in the analysis of receptor status in breast cancer. Having said that, findings around the use of NEDD8 ultimate buster 1 (NUB1) and