This diminution in the IFNc-IL-two co-generating subset has also been described in a modern publication in which Tcm phenotype Th1 memory cells (CCR7hiT-betloCXCR5+ ) had been deficient in their ability to co-make IFNc and IL-2 in comparison to Tem phenotype Th1memory cells (CCR7loT-bethi CXCR52)
Earlier studies have also shown the upkeep of the CD62Llo phenotype on endogenous memory...